Fri Feb 21 04:48:06 PM EST 2025 San Luis Obispo County Inland Central Coast- Including Lopez Lake, Nipomo, and San Luis Obispo 147 PM PST Fri Feb 21 2025 .TONIGHT...Mostly clear. Lows in the lower to mid 40s. .SATURDAY...Mostly sunny. Highs in the lower to mid 70s. .SATURDAY NIGHT...Mostly clear. Lows in the mid 40s to around 50. .SUNDAY...Sunny. Highs in the mid to upper 70s. .SUNDAY NIGHT...Mostly clear. Lows in the mid 40s to around 50. .MONDAY...Sunny. Highs in the upper 60s to mid 70s. .MONDAY NIGHT...Mostly clear. Lows around 50. .TUESDAY...Sunny. Highs in the mid 70s to around 80. .TUESDAY NIGHT...Mostly clear. Lows in the lower 50s. .WEDNESDAY...Sunny. Highs in the upper 70s to mid 80s. .WEDNESDAY NIGHT...Partly cloudy. Lows in the upper 40s to mid 50s. .THURSDAY...Mostly cloudy in the morning, becoming partly cloudy with a 20 percent chance of rain in the afternoon. Highs in the lower to mid 70s. .THURSDAY NIGHT...Mostly cloudy with a 20 percent chance of rain. Lows around 50. .FRIDAY...Mostly cloudy with a 20 percent chance of rain in the morning, becoming partly cloudy in the afternoon. Highs in the mid 60s to around 70.